The Functional Behaviors of Cosurfactant in Design of Self-nanoemulsifying Drug Delivery Systems
نویسندگان
چکیده
منابع مشابه
Formulation Design and Development of Self-Nanoemulsifying Drug Delivery Systems Containing a Hydrophobic Selective β1-Adrenoreceptor Blocker
The present work was aimed to design and develop self-nanoemulsifying drug delivery systems (SNEDDS) with the objective to overcome the problems associated with the delivery of talinolol, a hydrophobic and poorly bioavailable drugs having pH dependant solubility. The solubility of talinolol in various oils, surfactants, cosurfactants and aqueous phases were determined to identify and select the...
متن کاملDesign and optimization of self-nanoemulsifying drug delivery systems for improved bioavailability of cyclovirobuxine D
BACKGROUND The main purpose of this research was to design a self-nanoemulsifying drug delivery system (SNEDDS) for improving the bioavailability of cyclovirobuxine D as a poorly water-soluble drug. MATERIALS AND METHODS Solubility trials, emulsifying studies, and pseudo-ternary phase diagrams were used to screen the SNEDDS formulations. The optimized drug-loaded SNEDDS was prepared at a mass...
متن کاملthe role of type-d personality, social support and self-compassion in prediction of health behaviors in coronary heart disease patients
نظر به اهمیت و تاثیر روزافزون عوامل روانی – اجتماعی در سلامت جسمی و تاثیر عوامل روان شناختی در بروز بیماریهای مختلف از جمله بیماریهای قلبی و عروقی این پژوهش با هدف کلی بررسی ارتباط تیپ شخصیتی d ، حمایت اجتماعی و خود دلسوزی در پیش بینی رفتارهای بهداشتی بیماران کرونر قلبی و تعیین تفاوت بین بیماران کرونر قلبی با و بدون جراحی و افراد سالم در این متغیرها و رفتارهای بهداشتی آنان، انجام گرفت. جامعه آ...
15 صفحه اولIntroducing Self-Nanoemulsifying Drug Delivery System to Increase the Bioavailability of Oral Medications
Due to low cost, ease of administration, and lack need for trained personnel, the oral route is the most convenient and accessible way to design different medicines that could be simply consumed by patients. Regardless of the great benefits of this route, the main challenge in the bioavailability of oral medications is gastrointestinal instability. Nanotechnology is used to improve the solubili...
متن کاملformulation design and development of self-nanoemulsifying drug delivery systems containing a hydrophobic selective β1-adrenoreceptor blocker
the present work was aimed to design and develop self-nanoemulsifying drug delivery systems (snedds) with the objective to overcome the problems associated with the delivery of talinolol, a hydrophobic and poorly bioavailable drugs having ph dependant solubility. the solubility of talinolol in various oils, surfactants, cosurfactants and aqueous phases were determined to identify and select the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pharmaceutical Investigation
سال: 2010
ISSN: 2093-5552
DOI: 10.4333/kps.2010.40.5.263